Spliceostatin A|391611-36-2|ADC Payload-HuiDaCollection丨Dedicated to the establishment of a compound library of comprehensive intermediates and active ingredients

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Spliceostatin A

CAS： 391611-36-2

All products are only used for scientific research, instead of human or animal experiments.

Cat. No.：HD00427

Formula：C₂₈H₄₃NO₈

Mol. Weight：521.64

Purity：≥95%

Long Term Storage：Store in a tight container at -20℃

Description：RNA synthesis inhibitor

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Biological Activity

Spliceostatin A is a potent inhibitor of spliceosomes and exhibits excellent anticancer activity against multiple human cancer cell lines.Spliceostatin A treatment inhibits mitotic clonal expansion and adipogenesis.

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References

[1] Kaida D . Spliceostatin A treatment inhibits mitotic clonal expansion and adipogenesis[J]. Biochemical and Biophysical Research Communications, 2019, 514(3).

[2] Enantioselective Synthesis of a Cyclopropane Derivative of Spliceostatin A and Evaluation of Bioactivity.[J]. Organic letters, 2018.

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Spliceostatin A

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