CAS： 1405-41-0
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00359
Formula：C(19-21)H(39-43)N5O7 · H2SO4
Mol. Weight：561.65
Purity：≥95%
Long Term Storage：Store in a tight container at -20℃.
Description：It is used as topical and systemic broad-spectrum antibiotic with bactericidal action; also used in ophthalmic drugs.
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Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. It inhibits DNase I with an IC50 of 0.57 mm.
[1] Xu W, et al. A rapid and sensitive method for kinetic study and activity assay of DNase I in vitro based on a GO-quenched hairpin probe. Anal Bioanal Chem. 2016 May;408(14):3801-9.
[2] Rudin A, et al. Antibacterial activity of gentamicin sulfate in tissue culture. Appl Microbiol. 1970 Dec;20(6):989-90.
[3] Kumar CG, et al. Microbial biosynthesis and applications of gentamicin: a critical appraisal.
[4] Espersen F, et al. Effect of treatment with methicillin and gentamicin in a new experimental mouse model of foreignbody infection. Antimicrob Agents Chemother. 1994 Sep;38(9):2047-53.
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