CAS： 1405-10-3
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00308
Formula：C23H52N6O25S3
Mol. Weight：908.88
Purity：≥95%
Long Term Storage：Store in a tight container at -20℃.
Description：Aminoglycoside antibiotics；phospholipase C (PLC) inhibitor
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Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis.
[1] Sasseville D. Neomycin. Dermatitis. 2010;21(1):3-7.
[2] Hu GF. Neomycin inhibits angiogenin-induced angiogenesis. Proc Natl Acad Sci U S A. 1998;95(17):9791-9795.
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