CAS： 56377-79-8
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00222
Formula：C51H43N13O12S6
Mol. Weight：1222.36
Purity：≥95%
Long Term Storage：Store in a tight container at -20℃.
Description：Thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein
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Nosiheptide exhibited extremely potent activity against all contemporary MRSA strains tested including multiple drug-resistant clinical isolates, with MIC values 0.25 mg l(-1). Nosiheptide was also highly active against Enterococcus spp. Nosiheptide has been widely used as a feed additive for animal growth.
[1] Haste NM, et al. Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2012 Dec;65(12):593-8.
[2] Yu Y, et al. Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework. ACS Chem Biol. 2009 Oct 16;4(10):855-64.
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