CAS： 124759-75-7
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00058
Formula：C30H19NO9
Mol. Weight：537.48
Purity：≥95%
Long Term Storage：Store in a tight container at -20℃.
Description：DNA strand cleavage
Danomycin has strong killing effect on many kinds of tumor cells and the concentration of action is pg /mL. Bergman cyclization of the cycloenedi-drying portion of the enedifluorine class of antibiotics causes the formation of aromatic diradicals, which quickly rob the hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells.
[1] J. Antibiot. 1989 , 42. 1449 , 1991 , 44 , 1300 , J. Am.Chem. Soc. 1990 , 112: 3715 , 4040 , 1992.144:4107 , Sciences, 1992 , 256: 1172 , Tetrahedron Lett. 1990. 31: 1521.
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