CAS： 1566586-52-4 （Synonyms：PUM）
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00115
Formula：C17H26N8O9
Mol. Weight：486.44
Purity：≥95%
Long Term Storage：Store in a tight container at -20℃.
Description：RNA polymerase inhibitor
Pseudouridimycin (PUM) is a novel pseudouridine-contg. peptidyl-nucleoside antibiotic that inhibits bacterial RNA polymerase (RNAP) through a binding site and mechanism different from those of clin. approved RNAP inhibitors of the rifamycin and lipiarmycin (fidaxomicin) classes. PUM was discovered by screening microbial fermn. exts. for RNAP inhibitors.
[1]Sonia I Maffioli 1, Margherita Sosio 1, Richard H Ebright 2, Stefano Donadio 3, Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase, J Ind Microbiol Biotechnol. 2019 Mar;46(3-4):335-343.
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