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Location:Home > Products > ADC Payload > Exatecan

CAS: 171335-80-1

All products are only used for scientific research, instead of human or animal experiments.

Cat. No.:HD00141


Mol. Weight:435.45


Long Term Storage:Store in a tight container at 2-8℃.

Description:DNA topoisomerase I inhibitor

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Size Price, EXW Stock Quantity Add to Cart
10mg $205.00 In stock - 1 +
25mg $430.00 In stock - 1 +
100mg $1260.00 In stock - 1 +
1g $5150.00 In stock - 1 +
Biological Activity
Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
Product Data

[1] Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.

[2] Joto N, et al. DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant. Int J Cancer. 1997 Aug 7;72(4):680-6.

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