CAS: 2124-57-4 (Synonyms:Menaquinone-7)
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.:HD00001
Formula:C46H64O2
Mol. Weight:649.00
Purity:≥98%
Long Term Storage:Store in a tight container, protect from light.
Description:Increase the expression of osteocalcin, osteoprotegerin and RANKL mRNA
Size | Price, EXW | Stock | Quantity | Add to Cart |
---|---|---|---|---|
10mg | $168.00 | In stock | - 1 + | |
50mg | $355.00 | In stock | - 1 + | |
100mg | $568.00 | In stock | - 1 + | |
1g | Inquiry | In stock | - 1 + |
Vitamin K2(MK-7), belongs to a class of Vitamin-K2 homologs, is originally discovered as the anti-hemorrhagic factors. It is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins.Supplementation with Vitamin K2 (Menaquinone-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS).
[1] Peeters FECM, et al. Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients. 2018 Mar 21;10(4). pii: E386.
[2] Conly, J M., et al., 1994. The contribution of vitamin K2 (menaquinones) produced by the intestinal microflora to human nutritional requirements for vitamin K. The American journal of gastroenterology. 89(6): 915-23.
[3] Thijssen, H H., et al., 1994. Vitamin K distribution in rat tissues: dietary phylloquinone is a source of tissue menaquinone-4. The British journal of nutrition. 72(3): 415-25.
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