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Location:Home > Products > ADC Payload > FR901464
FR901464

CAS: 146478-72-0

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00006

Formula:C27H41NO8

Mol. Weight:507.62

Purity:≥90%

Long Term Storage:Store in a tight container at -80℃.

Description:RNA synthesis inhibitor

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Size Price, EXW Stock Quantity Add to Cart
2mg $390.00 In stock - 1 +
10mg $1050.00 In stock - 1 +
25mg $1560.00 In stock - 1 +
50mg $2650.00 In stock - 1 +
100mg $4000.00 In stock - 1 +
Biological Activity

FR901464 is an effective anti-cancer natural product, which can reduce the mRNA levels of oncogenes and tumor suppressor genes.

Product Data
References

[1] (a) Nakajima, H.; Sato, B.; Fujita, T.; Takase, S.; Terano,H.; Okuhara, M. J. Antibiot. 1996, 49, 1196–1203;(b) Nakajima, H.; Hori, Y.; Terano, H.; Okuhara, M.;Manda, T.; Matsumoto, S.; Shimomura, K. J. Antibiot.1996, 49, 1204–1211.

[2] Nakajima, H.; Takase, S.; Terano, H.; Tanaka, H. J.Antibiot. 1997, 50, 96–99.

[3] Thompson, C. F.; Jamison, T. F.; Jacobsen, E. N. J. Am.Chem. Soc. 2000, 122, 10482–10483.

[4] For our previous synthetic study, see: (a) Horigome, M.;Watanabe, H.; Kitahara, T. Tennen Yuki Kagobutsu Toronkai Koen Yoshishu 1999, 41, 73–78; Chem. Abstr.2000, 132, 676.

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