CAS： 1426953-21-0
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00002
Formula：C28H41NO9
Mol. Weight：535.63
Purity：≥95%
Long Term Storage：Store in a tight container at -20℃.
Description：DNA synthesis inhibitor
| Size | Price, EXW | Stock | Quantity | Add to Cart |
|---|---|---|---|---|
| 10mg | $220.00 | In stock | - 1 + | |
| 25mg | $450.00 | In stock | - 1 + | |
| 50mg | $720.00 | In stock | - 1 + | |
| 100mg | $1150.00 | In stock | - 1 + |
Thailanstatin A reveals low nanomolar to subnanomolar cytotoxicity against a variety of human cancer cell lines. The mechanism of action (MOA) of thailanstatin A is the inhibition of spliceosome assembly.
[1] Liu X, Biswas S, et al. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. J Nat Prod. 2013 Apr26;76(4):685-93.
[2] Puthenveetil S, Loganzo F, et al. Natural Product Splicing Inhibitors: A New Class of Antibody-Drug Conjugate (ADC) Payloads. Bioconjug Chem. 2016 Aug 17;27(8):1880-8.
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