Please enter your email
Send
Location:Home > Products > Nucleotide > 3'-O-Methylguanosine
3'-O-Methylguanosine

CAS: 10300-27-3 (Synonyms:3'-OMe-Guanosine; 3-OMG)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00036

Formula:C11H15N5O5

Mol. Weight:297.27

Purity:≥98.5%

Long Term Storage:Long term storage in a tight container at 2-8℃.

Description:Modified Nucleoside

Online Inquiry
Size Price, EXW Stock Quantity Add to Cart
100mg $56.00 In stock - 1 +
1g $138.00 In stock - 1 +
Biological Activity

3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. 

Product Data
References

[1] Morris GS, Simmonds HA, Davies PM: Use of biological fluids for the rapid diagnosis of potentially lethal inherited disorders of human purine and pyrimidine metabolism. Biomed Chromatogr. 1986 Jun;1(3):109-18.

[2] Yang TH, Hu ML: Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities. Nutr Cancer. 2006;55(2):224-31.

[3] Liu Z, Liu S, Xie Z, Blum W, Perrotti D, Paschka P, Klisovic R, Byrd J, Chan KK, Marcucci G: Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method. Nucleic Acids Res. 2007;35(5):e31. Epub 2007 Jan 30. 

Online Inquiry
Submit

You are the 145982 th Visitor

Phone:0086-571-86907218

Email:hdcsales@huidacollection.cn

Copyright © 2021 HuiDaCollection 浙ICP备20008217号 Designed by Wanhu

Back to top
Online Message
Submit