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Location:Home > Products > Nucleotide > Pseudouridine
Pseudouridine

CAS: 1445-07-4 (Synonyms:beta-Pseudouridine; psi-Uridine; 5-(beta-D-Ribofuranosyl)uracil)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00030

Formula:C9H12N2O6

Mol. Weight:244.20

Purity:≥98.5%

Long Term Storage:Store in a tight container at cool dry places.

Description:Modified Nucleoside

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Biological Activity

Pseudouridine (Ψ) is the most abundant modified nucleoside in RNA and has been referred to as the ‘fifth nucleoside’. Pseudouridine is found in a plethora of positions within tRNAs as well as in a number of positions in rRNAs and in snRNAs. Pseudouridine is a C-glycosyl pyrimidine that consists of uracil having a β-D-ribofuranosyl residue attached at position 5. The C-glycosyl isomer of the nucleoside uridine. It has a role as a fundamental metabolite. 

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References

[1] RNA Modification, Katherine M. McKenney, ... Juan D. Alfonzo, The Enzymes, 2017.

[2] Carlile TM, et al. Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells. Nature. 2014 Nov 6;515(7525):143-6.

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