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Location:Home > Products > Others > Ginsenoside Rb1
Ginsenoside Rb1

CAS: 41753-43-9

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00193

Formula:C54H92O23

Mol. Weight:1109.29

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:Main constituent of the root of Panax ginseng

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Biological Activity
Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Alsoit can inhibit IRAK-1 activation and phosphorylation of NF-κB p65.
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References

[1] Joh EH, et al. Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation--the key step of inflammation. Biochem Pharmacol. 2011 Aug 1;82(3):278-86.

[2] Zhang J, et al. Ginsenosides Regulate PXR/NF-κB Signaling and Attenuate Dextran Sulfate Sodium-Induced Colitis. Drug Metab Dispos. 2015 Aug;43(8):1181-9.

[3] Jiang Y, et al. Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice. Oxid Med Cell Longev. 2015;2015:843721.

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