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Location:Home > Products > Others > 4-Hydroxyderricin
4-Hydroxyderricin

CAS: 55912-03-3

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00188

Formula:C21H22O4

Mol. Weight:338.4

Purity:≥95%

Long Term Storage:Store in a tight container between 2-8℃, protect from light.

Description:Major active ingredients of Angelica keiskei Koidzumi, potent selective MAO-B inhibitor.

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Biological Activity

Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity, has antidepressant activity.

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References
[1] Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40.
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