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Location:Home > Products > Others > Sitagliptin
Sitagliptin

CAS: 486460-32-6

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00325

Formula:C16H15F6N5O

Mol. Weight:407.31

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:Novel anti-type 2 diabetes drugs

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Biological Activity
Sitagliptin is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts.
Product Data
References

[1] Thomas, L., et al. (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors. J Pharmacol Exp Ther. 2008 Apr;325(1):175-82.

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