14-Deoxyandrographolide

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CAS： 4176-97-0

All products are only used for scientific research, instead of human or animal experiments.

Cat. No.：HD00177

Formula：C₂₀H₃₀O₄

Mol. Weight：334.45

Purity：≥95%

Long Term Storage：Store in a tight container at -20℃.

Description：Bioactive compound of Andrographis paniculata

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Biological Activity

14-Deoxyandrographolide is a biologically active compound of Andrographis paniculata. It desensitizes hepatocytes to TNF-α-mediated apoptosis by releasing TNFRSF1A, and has a liver-protecting effect.

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References

[1] Roy DN, et al. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Br J Pharmacol. 2010 Aug;160(7):1823-43.

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14-Deoxyandrographolide

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