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Formononetin

CAS: 485-72-3 (Synonyms:Biochanin B; Flavosil; Formononetol)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00283

Formula:C16H12O4

Mol. Weight:268.26

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:Flavonoids, which exist in many plants such as astragalus and spatholobi

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Biological Activity

Formononetin (Formononetol; Flavosil) is a bioactive component extracted from the red clover; inhibits the proliferation of DU-145/PC-3 cells in a dose-dependent manner.

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References

[1] Liu XJ, et al. Up-regulating of RASD1 and apoptosis of DU-145 human prostate cancer cells induced by formononetin in vitro. Asian Pac J Cancer Prev. 2014;15(6):2835-9.

[2] Zhang X, et al. Formononetin induces apoptosis in PC-3 prostate cancer cells through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt pathway. Nutr Cancer. 2014;66(4):656-61.

[3] Chen J, et al. Formononetin induces cell cycle arrest of human breast cancer cells via IGF1/PI3K/Akt pathways in vitro and in vivo. Horm Metab Res. 2011 Sep;43(10):681-6.

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