CAS: 18378-89-7 (Synonyms:Plicamycin)
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.:HD00103
Formula:C52H76O24
Mol. Weight:1085.15
Purity:≥95%
Long Term Storage:Store in a tight container at -20℃.
Description:DNA/RNA polymerase inhibitor
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Mithramycin is an antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity, a selective specificity protein 1 (Sp1) inhibitor. Mithramycin inhibits the growth of various cancers by decreasing Sp1 protein.
[1] Choi ES, et al. Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer. Sci Rep. 2014 Nov 24;4:7162.
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