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Thymidine

CAS: 50-89-5 (Synonyms:DThyd; NSC 21548)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00127

Formula:C10H14N2O5

Mol. Weight:242.23

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:Building blocks of nucleic acid

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Biological Activity

Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

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References

[1] Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17).

[2] FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.

[3] Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan;13(1):85-93.

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