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Location:Home > Products > Nucleotide > 5-Ethynyl-2'-Deoxyuridine
5-Ethynyl-2'-Deoxyuridine

CAS: 61135-33-9

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00077

Formula:C11H12N2O5

Mol. Weight:252.22

Purity:≥95%

Long Term Storage:Store in a tight container between 2-8℃, protect from light.

Description:Building blocks of nucleic acid

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Biological Activity

5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation.

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References

[1] Chenbo Zeng, et al. Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system. Brain Res. 2010 Mar 10;1319:21-32. 

[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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