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Location:Home > Products > Nucleotide > 5-Iodo-2'-Deoxyuridine
5-Iodo-2'-Deoxyuridine

CAS: 54-42-2 (Synonyms:5-IUdR; IdUrd)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00076

Formula:C9H11IN2O5

Mol. Weight:354.10

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:Building blocks of nucleic acid

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Biological Activity

Idoxuridine (5-Iodo-2′-deoxyuridine) is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.

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References

[1] Seth AK, et al. Topical liposomal gel of idoxuridine for the treatment of herpes simplex: pharmaceutical and clinical implications. Pharm Dev Technol. 2004 Aug;9(3):277-89. 

[2] Fauth E, et al. Comparison of spontaneous and idoxuridine-induced micronuclei by chromosome painting. Mutat Res. 1999 Apr 6;440(2):147-56. 

[3] Otto SE. Radiopharmaceuticals (Strontium 89) and radiosensitizers (idoxuridine). J Intraven Nurs. 1998 Nov-Dec;21(6):335-7. 

[4] De Clercq E. Specific targets for antiviral drugs. Biochem J. 1982;205(1):1-13.

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