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Location:Home > Products > Antifungal > Nikkomycin
Nikkomycin

CAS: 59456-70-1

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00439

Formula:C20H25N5O10

Mol. Weight:495.4

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃

Description:peptidyl nucleocide antibiotics

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Biological Activity

Nikkomycins are competitive inhibitors of chitin synthase and inhibit the growth of filamentous fungi, insects, acarids and yeasts. The gene cluster responsible for biosynthesis of nikkomycins has been cloned and the biosynthetic pathway was elucidated at the genetic, enzymatic and regulatory levels.

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References

[1] Feng C , Ling H , Du D , et al. Novel nikkomycin analogues generated by mutasynthesis in Streptomyces ansochromogenes[J]. Microbial Cell Factories, 2014, 13.

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