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Location:Home > Products > Biochemical Reagent > G418
G418

CAS: 49863-47-0

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00232

Formula:C20H40N4O10

Mol. Weight:496.55

Purity:≥95%

Long Term Storage:tore in a tight container at -20℃.

Description:Aminoglycoside antibiotic

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Biological Activity

G418 (Geneticin) is an aminoglycoside antibiotic similar in structure to gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

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References

[1] Holbrook Selina Y. L., Gentry Matthew S., Tsodikov Oleg V., Garneau-Tsodikova Sylvie. Nucleoside triphosphate cosubstrates control the substrate profile and efficiency of aminoglycoside 3′-O-phosphotransferase type IIa, MedChemComm, 2018

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