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Location:Home > Products > Antitumor > Epothilone A
Epothilone A

CAS: 152044-53-6 (Synonyms:Epo A)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00224

Formula:C26H39NO6S

Mol. Weight:493.66

Purity:≥95%

Long Term Storage:tore in a tight container at -20℃.

Description:A competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers

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Biological Activity

Epothilone A, like paclitaxel, induced to form at low temperatures and without and/or -associated proteins. Epothilone A is a competitive inhibitors of the of [3H]paclitaxel to polymers.

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References

[1] Kowalski RJ, et al. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)). J Biol Chem. 1997 Jan 24;272(4):2534-41.

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