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Location:Home > Products > Biochemical Reagent > Aflatoxin B1
Aflatoxin B1

CAS: 1162-65-8

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00097

Formula:C17H12O6

Mol. Weight:312.27

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:Class 1A carcinogen

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Biological Activity

Aflatoxin B1 (AFB1) is a class 1A carcinogen, which mainly induces the third G-->T transversion of codon 249 of the p53 tumor suppressor gene, leading to mutations.

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References

[1] Aguilar F, et al. Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8586-90.

[2] Gizachew D, et al. Aflatoxin B1 (AFB1) production by Aspergillus flavus and Aspergillus parasiticus on ground Nyjer seeds: The effect of water activity and temperature. Int J Food Microbiol. 2019 May 2;296:8-13.

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