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Location:Home > Products > Antitumor > Didemnin B
Didemnin B

CAS: 77327-05-0

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00004

Formula:C57H89N7O15

Mol. Weight:1112.35

Purity:≥95%

Long Term Storage:Store in a tight container at -20°C.

Description:A depsipeptide, antiviral and antineoplastic

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Biological Activity

Didemnin B is a cyclic depsipeptide with antiviral and antitumor activity.

Product Data
References

[1] Biologically active depsipeptides extracted from a Caribbean tunicate (sea squirt) family Didemnidae, genus Trididemnum. First marine natural product to enter clinical trials as antineoplastic. The three components, didemnins A, B and C are weakly basic compds with antiviral, antitumor activity. Didemnin A is the most abundant, whereas didemnin B is generally the most active.  

[2] Isoln and bioactivity: K. L. Rinehart, Jr. et al., Science 212, 933 (1981).  

[3] Extraction and purification:  K. L. Rinehart, Jr., EP 48149; idem, US 4493796 (1982, 1985 both to Univ. Illinois).  

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