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Location:Home > Products > Others > Ginsenoside Rd
Ginsenoside Rd

CAS: 52705-93-8 (Synonyms:Gypenoside VIII)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00194

Formula:C48H82O18

Mol. Weight:947.15

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:26S proteasome inhibitor and TRPm7 antagonist

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Biological Activity

Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Ginsenoside Rd may have properties that inhibit or prevent the growth of tumors.

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References

[1] Chen, C.F., Chiou, W.F., and Zhang, J.T. Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium. Acta.Pharmacol.Sin. 29(9), 1103-1108 (2008).

[2] Wang, Y., Li, X., Wang, X., et al. Ginsenoside Rd attenuates myocardial ischemia/reperfusion injury via Akt/GSK-3β signaling and inhibition of the mitochondria-dependent apoptotic pathway. PLoS One 8(8), e70956 (2013).

[3] Liu, X., Wang, L., Wen, A., et al. Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur.J.Neurol. 19(6), 855-863 (2012).

[4] Song, S.B., Tung, N.H., Quang, T.H., et al. Inhibition of TNF-α-mediated NF-κB transcriptional activity in HepG2 cells by dammarane-type saponins from Panax ginseng leaves. J.Ginseng Res. 36(2), 146-152 (2012).

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