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Location:Home > Products > Others > 4'-Methylchrysoeriol
4'-Methylchrysoeriol

CAS: 4712-12-3

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00167

Formula:C17H14O6

Mol. Weight:314.29

Purity:≥95%

Long Term Storage:Store in a tight container at -20℃.

Description:Cytochrome P450 enzyme (P450) inhibitor

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Biological Activity

4'-Methylchrysoeriol is a potent inhibitor of P450 enzymes, particularly for P450 1B1, with an IC50 of 19 nM for human P450 1B1-dependent EROD.

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References

[1] Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22(7):1325-33.

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