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Location:Home > Products > Nucleotide > 2'-Fluoro-2'-Deoxyguanosine
2'-Fluoro-2'-Deoxyguanosine

CAS: 78842-13-4

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00082

Formula:C10H12FN5O4

Mol. Weight:285.23

Purity:≥95%

Long Term Storage:Store in a tight container between 2-8℃.

Description:Building blocks of nucleic acid

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Biological Activity

2'-Fluoro-2'-Deoxyguanosine, a nucleoside analog, is a potent inhibitor of influenza virus A and B strains. 2'-Fluoro-2'-Deoxyguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation.

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References

[1] Tisdale M, et, al. Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. Antimicrob Agents Chemother. 1995 Nov;39(11):2454-8. 

[2] Jakeman KJ, et, al. Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother. 1994 Aug;38(8):1864-7.

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