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Location:Home > Products > Animal Health > Doramectin
Doramectin

CAS: 117704-25-3

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00142

Formula:C50H74O14

Mol. Weight:899.11

Purity:≥95%

Long Term Storage:Store in a tight container between 2-8℃.

Description:Major inhibitory neurotransmitter

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Biological Activity

Doramectin is an antiparasitic drug for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.

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References

[1] Lumaret JP, Errouissi F, Floate K, Römbke J, Wardhaugh K. A review on the toxicity and non-target effects of macrocyclic lactones in terrestrial and aquatic environments. Curr Pharm Biotechnol. 2012 May;13(6):1004-60. Review. PubMed PMID: 22039795; PubMed Central PMCID: PMC3409360.

[2] Davey RB, Pound JM, Klavons JA, Lohmeyer KH, Freeman JM, Olafson PU. Analysis of doramectin in the serum of repeatedly treated pastured cattle used to predict the probability of cattle fever ticks (Acari: Ixodidae) feeding to repletion. Exp Appl Acarol. 2012 Apr;56(4):365-74. doi: 10.1007/s10493-012-9525-1.

[3] Wang XJ, Zhang J, Wang JD, Huang SX, Chen YH, Liu CX, Xiang WS. Four new doramectin congeners with acaricidal and insecticidal activity from Streptomyces avermitilis NEAU1069. Chem Biodivers. 2011 Nov;8(11):2117-25. doi: 10.1002/cbdv.201000295.

[4] Gordana Panic, et al. Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni. PLoS Negl Trop Dis. 2015 Jul 31;9(7):e0003962.

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