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Location:Home > Products > Antitumor > Talisomycin A
Talisomycin A

CAS: 65057-90-1

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00061

Formula:C68H110N22O27S2

Mol. Weight:1731.86

Purity:≥95%

Long Term Storage:Store in a tight container under room temperature.

Description:DNA strand cleavage

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Biological Activity

Antitumor antibiotic complex and third generation analog of bleomycins, q.v., produced by Streptoalloteichus hindustanus E 465-94. Prodn, isoln, properties of the major components, tallysomycins A and B.

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References

[1] Pharmacokinetics of tallysomycin and bleomycin in the beagle dog. Strong JE, Schurig JE, Issell BF, Kramer WG, Tavel AF, Florczyk AP, Crooke ST.Cancer Treat Rep. 1979 Nov-Dec; 63(11-12):1821-7.

[2] Comparison of the sequences at specific sites on DNA cleaved by the antitumor antibiotics talisomycin and bleomycin. Mirabelli CK, Beattie WG, Huang CH, Prestayko AW, Crooke ST.Cancer Res. 1982 Apr;42(4):1399-404.

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