CAS： 186692-73-9
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00028
Formula：C26H39NO5S
Mol. Weight：477.66
Purity：≥98%
Long Term Storage：Store in a tight container between 2-8℃.
Description：Microtubule stabilizer
Epothilone C belong to the epothilone family of compounds which is a group of polyketide natural products produced by the myxobacterium Sorangium cellulosum. Mechanism wise similar to taxanes, epothilones fight cancer cells by interfering with tubulin.
[1] Cheng K, Bradley T, Budman D R, et al. Novel microtubule-targeting agents - the epothilones[J]. Biologics: Targets & Therapy, 2008, 2(4): 789-811.
[2] Boddy C N, Schneider T L, Hotta K, et al. Epothilone C Macrolactonization and Hydrolysis Are Catalyzed by the Isolated Thioesterase Domain of Epothilone Polyketide Synthase[J]. Journal of the American Chemical Society, 2003, 125(12): 3428-3429.
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