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Location:Home > Products > Antitumor > Dihydrocarminomycin
Dihydrocarminomycin

CAS: 62182-86-9

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00026

Formula:C26H29NO10    

Mol. Weight:515.52

Purity:≥98%

Long Term Storage:Store in a tight container at -20℃.

Description:Anthracycline antibiotic

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Biological Activity

Dihydrocarminomycin is an anthracycline antibiotic that intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.

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References

[1] Shepelevtseva N G, Belova I P, Vertogradova T P, et al. Comparative study of the cardiotoxicity of the anthracycline antibiotics, rubomycin, carminomycin and dihydrocarminomycin, in experiments on white mice. Antibiotiki. 1978 Jan;23(1):78-87.

[2] Povarov L S,Shorin V A,Bazhanov V S,Shepelevtseva N G.Preparation of dihydrocarminomycin and a comparison of its antitumor activity with the activity of carminomycin.[J]. Antibiotiki,1976,21(11):1008-11.

[3] Dudnik IuV, Ostanina LN. Interaction with DNA of semisynthetic carminomycin and rubomycin derivatives. Antibiotiki. 1983 Jan;28(1):31-6.

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