CAS： 93908-02-2
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00025
Formula：C27H21Cl2N3O7
Mol. Weight：570.38
Purity：≥98%
Long Term Storage：Store in a tight container at -20℃.
Description：DNA topoisomerase I Inhibitor
Rebeccamycin is a microbial metabolite and a well-known topoisomerase I inhibitor. It is used as an antitumor drug.
[1] Pommerehne K, Walisko J, Ebersbach A, et al. The antitumor antibiotic rebeccamycin—challenges and advanced approaches in production processes[J]. Applied microbiology and biotechnology, 2019, 103(9): 3627-3636.
[2] Schwandt A, Mekhail T, Halmos B, et al. Phase-II trial of rebeccamycin analog, a dual topoisomerase-I and-II inhibitor, in relapsed “sensitive” small cell lung cancer[J]. Journal of Thoracic Oncology, 2012, 7(4): 751-754.
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