CAS: 1149-99-1
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.:HD00064
Formula:C15H20O4
Mol. Weight:264.32
Purity:≥95%
Long Term Storage:Store in a tight container at -20℃.
Description:DNA Alkylator
Illudin S is a cytotoxic Illudin, a genetically toxic natural sesquiterpene with strong anti-tumor and anti-viral activities. Illudin S blocks the G1-S phase interface of the human leukemia cell cycle.
[1] Glatt H, Pietsch KE, Sturla SJ, Meinl W. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Arch Toxicol. 2014 Jan;88(1):161-9.
[2] Tanaka K, Inoue T, Kadota S, Kikuchi T. Metabolism by rat liver cytosol of illudin S, a toxic substance of Lampteromyces japonicus. II. Characterization of illudin S-metabolizing enzyme. Xenobiotica. 1992 Jan;22(1):33-9.
[3] Pietsch KE, van Midwoud PM, Villalta PW, Sturla SJ. Quantification of acylfulvene- and illudin S-DNA adducts in cells with variable bioactivation capacities. Chem Res Toxicol. 2013 Jan 18;26(1):146-55.
You are the 1661994 th Visitor
Phone:0086-571-86907218
Email:hdcsales@huidacollection.cn
Copyright © 2021 HuiDaCollection 浙ICP备20008217号 Designed by Wanhu