CAS： 1404-15-5 （Synonyms：Nogalamycine；Nogalamycinum；Nogalomycin）
All products are only used for scientific research, instead of human or animal experiments.
Cat. No.：HD00110
Formula：C39H49NO16
Mol. Weight：787.80
Purity：≥95%
Long Term Storage：Store in a tight container at -20°C.
Description：DNA topoisomerase I Inhibitor
| Size | Price, EXW | Stock | Quantity | Add to Cart |
|---|---|---|---|---|
| 25mg | $1080.00 | In stock | - 1 + | |
| 100mg | Inquiry | In stock | - 1 + |
Nogalamycin is an anthracycline antibiotic produced by the soil bacteria Streptomyces nogalater. It is a potent antibiotic against Gram-positive bacteria and also works as an antitumor agent presumably by intercalating DNA to disrupt DNA replication and transcription.
[1] Vilja Siitonen 1, Magnus Claesson, Pekka Patrikainen, Maria Aromaa, Pekka Mäntsälä, Gunter Schneider, Mikko Metsä-Ketelä, Identification of late-stage glycosylation steps in the biosynthetic pathway of the anthracycline nogalamycin, Chembiochem. 2012 Jan 2;13(1):120-8. doi: 10.1002/cbic.201100637. Epub 2011 Nov 25.
[2] Yuta Tsunematsu, ... Kenji Watanabe, in Comprehensive Natural Products III, 2020, Structural Diversity and Biosynthesis of Natural Products: Polyketides, Terpenes
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