Please enter your email
Location:Home > Products > Animal Health > Apicidin

CAS: 183506-66-3 (Synonyms:OSI 2040)

All products are only used for scientific research, instead of human or animal experiments.

Cat. No.:HD00070


Mol. Weight:623.78


Long Term Storage:Store in a tight container at -20℃.

Description:HDAC inhibitor

Online Inquiry
Size Price, EXW Stock Quantity Add to Cart
10mg Inquiry Inquiry  - 1 +
25mg Inquiry Inquiry  - 1 +
Biological Activity

Apicidin is a fungal metabolite shown to exhibit antiparasitic activity by the inhibition of histone deacetylase,showed a broad spectrum of antiproliferative activity against various cancer cell lines.

Product Data

[1] J W Han 1, S H Ahn, S H Park, S Y Wang, G U Bae, D W Seo, H K Kwon, S Hong, H Y Lee, Y W Lee, H W Lee, Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin, Cancer Res. 2000 Nov 1;60(21):6068-74.

[2] Choi JH, Lee JY, Choi AY, Hwang KY, Choe W, Yoon KS, Ha J, Yeo EJ, Kang I. Apicidin induces endoplasmic reticulum stress- and mitochondrial dysfunction-associated apoptosis via phospholipase Cγ1- and Ca (2+)-dependent pathway in mouse Neuro-2a neuroblastoma cells. Apoptosis. 2012 Dec;17(12):1340-58.

[3] Ahn MY, Kang DO, Na YJ, Yoon S, Choi WS, Kang KW, Chung HY, Jung JH, Min do S, Kim HS. Histone deacetylase inhibitor, apicidin, inhibits human ovarian cancer cell migration via class II histone deacetylase 4 silencing. Cancer Lett. 2012 Dec 28;325(2):189-99. 

Online Inquiry

You are the 759411 th Visitor


Copyright © 2021 HuiDaCollection 浙ICP备20008217号 Designed by Wanhu

Back to top
Online Message