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Location:Home > Products > Antitumor > Distamycin A
Distamycin A

CAS: 39389-47-4 (Synonyms:Distamycin)

All products are only used for scientific research, instead of human or animal experiments.


Cat. No.:HD00023

Formula:C22H27N9O4

Mol. Weight:481.51

Purity:≥90%

Long Term Storage:Store in a tight container at -20℃.

Description:Anticancer antibiotic,antiviral and antiprotozoal activity.

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10mg $950.00 In stock - 1 +
100mg Inquiry In stock - 1 +
Biological Activity
Distamycin is an antibiotic that binds the minor groove of duplex DNA at AT‐rich regions and induces a specific activation of transcriptional initiation by binding to non-alternating AT sequences in the spacer DNA.
Product Data
References

[1] Cocco M J, Hanakahi L A, Huber M D, et al. Specific interactions of distamycin with G‐quadruplex DNA[J]. Nucleic acids research, 2003, 31(11): 2944-2951.

[2] Khalaf A I, Waigh R D, Drummond A J, et al. Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity[J]. Journal of medicinal chemistry, 2004, 47(8): 2133-2156.

[3] Dorn A, Affolter M, Müller M, et al. Distamycin‐induced inhibition of homeodomain‐DNA complexes[J]. The EMBO journal, 1992, 11(1): 279-286.

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